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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88a61ff1b0b28d01eac66512e47f7da1c42fcab555ad879c92fcf56125bcc8e1' 
  AND token = '8TzHIWX2d7CGTICPwYExerDHWIok05+pLiB4XGarSpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}