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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e90d801612286403c77eaf324340ae97cb91ca79c5aff56ea8f1eea7e2e7c3' 
  AND token = 'HOkkPuCFs9/2BNBWqJ9Jt3pHnGdRv5C3vEksCn275rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}