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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb5de827b89763de9d3bc374222f10c2a7661e471ed97d1f9216b7252daad286' 
  AND token = 'Yr6TOjyfLsCqWUC/g8sdVPtMTxVVXj/8VXEfRskthlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}