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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5334f2434d200571557986b1089bc1cdfd251c3e27ebdc2988a012be5396cf' 
  AND token = 'hiQ0w0T6F7DY+hxwUJT6M5jZ+XQO15JeIQEBJh4ZMZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}