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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160450d1238cbe710c30b32baeb5d3e9b6633d3b5fd219e07637e234a8e01efd' 
  AND token = 'oCgiCkEuhFf2rH/EJW2U7/23WPlkKEuXy2OOJ6/uaG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}