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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e68d8e1182c95c98b17eeb3d27b60d9baac393f7bc59e1f76850a3dcf1d2bf' 
  AND token = 'Yu8zBiDPOa2icqj/uoNmNKMxNYlipjGehFlPmzxQ/jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}