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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f26c4ee0363281821648aaaf5e14be1ff0670698d42c917dec1ef5551c2a42' 
  AND token = 'A/yc3JKmoZHpAymBuDTcgFM9MZX6goPY68qMjqDzjOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}