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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7f043437c9b5493c07a0096680825a5da18bbaabb7e37cbe3e513ac172c730' 
  AND token = 'MBPM9mXiqnoV3Fp/7mDUFDtNgyXPom+Gz1jn8yitSvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}