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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '813e7ac637195c7c60ab63e743383ffa641e02baa55f030c639931820cfde517' 
  AND token = 'VXTRtg5rl8XVJqM+TzaYd1OHBNJDgnrmGI1lI37tw0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}