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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ed91379ae48a2615b628cb3286aee949212d31ec8a38f152cf95eb2b1fd2ce5' 
  AND token = 'KPmStnSmv/1dmlSCyBAwAI9G5kZ7GnmcCwBmhdGFx2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}