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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c1afa44e24490f18b30294e4c2284109bc4cb515301e1dc8c248899a752aac' 
  AND token = '4KuHem3OMDYDaRaqJqI+4Uul3ZpxJeygn0Hu8PvcxPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}