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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c25121d822f11080e2e816d7e2b713ca3c71914680a09889674264756421cea' 
  AND token = 'cYAjfAh2vruTaSIBDirKn5kotUSqQMVzR7rfiIyf5gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}