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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27fcab613b4545bb36e6a0eeb21ee2d35e3381ace5193d6d68e918d7c92e434' 
  AND token = 'E3h8vbKxJizV1mZapG5sTdLksj9U7fbz24kTnCad2/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}