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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bcd08b680fe104c048e773039df325669a2ef6f37ffbd10c227ea2e1b181454' 
  AND token = '0qybKKVmkAG9F5G0Pe5bbJz8skMK2P19atBUFCl61dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}