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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50747e2300980d4e90d2bd4a011e159fc8305d280e136a6cac81ca28a677d7e5' 
  AND token = '+bcYXHMFGKooqUNJXFcE283itOInSV4KZmup77Fw8hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}