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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88b40c8c52094b072aaeac0e447242856b250368d8cdaf2d27f997f659236ab' 
  AND token = 'SyK3E+LdNtB7Sz8E0FfLeN9l8942Ulpo5PsynElyUkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}