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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c53b968f878573c2fde2d05169ba88b4716f4e9f77b7fb39d65a4597768f6f' 
  AND token = 'FM1Cy35cUe/XxYaoZM69xfJ2Unzc9Q3O0JN6BFPSUW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}