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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344d50955c384d3cc259b4478ac23caf4961e242f8e9d0d4c5b82aa379c9ffb3' 
  AND token = 'IN0Dm2FULp+tYtlUyzP518LGaBofIRWUkRzk0xMDlJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}