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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4078ecd5b65e4db739ac4477eafdf1dc1b470916f1aedc0d8b8a23e0bd96448b' 
  AND token = 'wGAsjanlvVX5ko7MNyVmWUlcFBmEt3E0e4IPXZuzVjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}