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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd6ffc025782f8e6c1d516cc0ab50dc8a60c03197dd60f5070e2d7514dfea3b' 
  AND token = '7uRjhCACplZHG7ppd8OtYf4I3xxAkyRXe6ZQo9uKKL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}