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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1609406ee2645eed7406fd126d746f48d24e3b0f9b88229f1f2eb03ecd839db7' 
  AND token = '1bG03VWFv0Tm1GR7GvTBlbFUZGTU1W0HkG8ZxJCRuWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}