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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59f8c58d1d110290b12d7c3f2e99e94112933afa2d7acebf98533fa5a720ca2f' 
  AND token = 'sBIia2iGyuDvjYMfBQ+6k8ShN/WbAQzSMHdvq4kWnmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}