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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e0432aa5680312f770f4c064c73755b4267feb9834d5c6585ce0f7b601f7d8' 
  AND token = 'yc+6JmR+gwecaFQ/7oCPb32QcmdArzlmKDpdvgoXq4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}