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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22e7375f722125ca5a0ebf3e03c762fb271a6c64371896ab961d56fa7b9ef3b' 
  AND token = 'CgEe/q5IpDmJuyGOVCwdkU09G7sIIL4DgBR3apLjpHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}