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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f607eed52fd7782c5dede2a2156c63f3bfd0c3a59036357debc813e5355fb7' 
  AND token = 'Pt/u4ZfsdbFAFralzxyRstmLOya+Ji56Z3bk9TrIE8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}