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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fec4e366c15c18e6a215269f66f635b077f83bcdadb253878d99cf6cf3868d7d' 
  AND token = 'REgZwLVLEavfrbMINU6eCZVYDZmMdHqa1KVZf8in+Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}