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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e384adf11503bd00ee53d2a6798cdb43cc8dfa2cdf85879d77f4f79b8ce3a9d' 
  AND token = 'zBT8idH/a/aagJPpvZi3174rcADGkJxEaxrQSYz1c9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}