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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7481ecef6a45ea7d171ab140d021c510411a0f056dbd3c0151a6f113c2262d77' 
  AND token = 'uV3TmUpiIE3C093dxgzxApjiPLV9wDg5jW26Lo9CaN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}