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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d8ba608208d3b1590d951a7a6e59421252c04a7e28a606119caf1b656b6720' 
  AND token = 'a2PF9wbvvE0GkClujsotagg+WGAW8u6x9TvtpGXSrBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}