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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be824b0f83c36ff81a8c2eab27ae544ad12577ca48cd5a8354b7b0fce1c3914d' 
  AND token = '+1DU82WtWjLRoWAXPcvj7G2W0Z1hoZLncjd0FkQXk50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}