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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14bfdd1c42b52aa3c2fc9040b542a9a3ec79d8b7da6f5028081d29515474ca97' 
  AND token = 'EEDG6EjivTfXq8PHR4jyt4xhBMZ7q4StZXxqiHzl2Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}