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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eb527019fcee0e9ef485d3c010177e135e59b4e8fe201dd2ea9f652df3ef918' 
  AND token = 'foGweBEkMaDyYQUvDffEf2P4QDxQT3o0j2szhLRIREU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}