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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '504453848df85edf8ed2c4d691325a6234adb0b438af6bc26b1c8d63c70ca91c' 
  AND token = 'tcaENJQ1BOFAAC2IEeQ5/qdO4Oit/XHJOhFX+g5Q1Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}