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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a339630aec7de71388cfeb382452b5eeab331d1e3f65b3eb0349e6d624abb4db' 
  AND token = 'b1Bbs+G9EhcAC7V0dS52GAX9c2zoICJWaAhgupP9iGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}