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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97121f798f9819fe335ddc01bd6533ce80eb9ee78706a9473e3d98010ec515f1' 
  AND token = 'ACP9ttfu38w0fkaTKYcbc4SNA1GlpotMiKRLjdDqYV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}