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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ccea1c46d5f0bf1109dae7e6a41d7bb73e2b4efa471c1e231a5d0535f3277b6' 
  AND token = 'o2rzOBEv5ADm+GyclIiq/RnSCH2QKHPT6KtXoMicWTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}