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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08535720271ab1759b5630593b13ad0384758067ef99bf52776b5a77c52a7031' 
  AND token = 'lDGX2rWPtH7i5IO5CMWxaKwfyrf0hrMQ6s9lBTWdFcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}