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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d94d1d1f7fe1d72a9af9f2f6fee1efd91fbf801c6bea8517f443e513835ea3' 
  AND token = 'zaGGPFx7cRuKE0xlh2xY6wrYcQYYEbu35+OBqz5kZlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}