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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95def2e5fba3dc00bf0887c4fb338f2b8ee34da889142a066030361b989e5780' 
  AND token = '4aQiEQaz/k8+r2pUb+ZyRzo8c+iRErwmvLCMUAnHHtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}