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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be8d36df8709bd10122c51ed72255922463c74e550f68a2935ba437a06f58d0' 
  AND token = '0pzEU3+ilgzC20+NZ+rJARXWKhJeo2nMyxmFMiAK3gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}