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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1556e6a20084b11f8d188f9f23cb553a2c93bd734e4db9baf1bf12cee5d49cf5' 
  AND token = 'qE8sOt6Ks75VIma+pw5DeEJGJKuFRmpJ8qbjx8s6QTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}