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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15cb3c75f8f4b884909a890f696c334afa139b1369af6919d5d2e507d416c969' 
  AND token = 'A1S7oF0QuFznfVwdAFLE88ltNX2D+kJFBCd0nGx5Gcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}