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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387cd0fe664d2772310b07ae42f5227dc38533b73d344ea80f5a8f470ad07d1d' 
  AND token = 'Z2617dKLkuNTvMh5plp1fpg7vdmikSW/RjStHCDXA+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}