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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10cfc9d948a0cb6f465a7f062fb1ef04453aa3c724b397c9c016efaf45d9d81f' 
  AND token = 'hf6zDPVlRU5gWe/Az14sj3HvgQ3s9LuWaYf20hpwoCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}