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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6115ac0b87263c227d578059154f09c87fd7af75a1984efc85172a8ab2d93e21' 
  AND token = 'Z7yTYVoWZNOeCLA7ae5SLq9NRBh5ZUt/T+pyCu1gHco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}