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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33e4c40cac1d9e5df4f1a9461b4f11b6aed3905d4d3a41dfca4cb58e0915426' 
  AND token = 'N0xustPHecTKgpikUH3SOql8NAu0hW3Q1ng8aFW4pT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}