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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c42974cce41291cae29f1a8e3ac7d86b554df3dede078303f68a76202231091' 
  AND token = 'AG0vpTYMR3harsVQ0J0NABqOs3aSaa/pVufe6FlhFb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}