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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e44ab83ce5e48ef5f01be236309d0f67d37352103eb9b0ecad9f259c0403e2' 
  AND token = 'ekpbuLODW3pY+BWyJYmdSmy9+ReD5TJMcfTgun0xerw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}