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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b448bd02ea14b4cd4ebf5448b46722fb42ea9c37813a80723e4114160a424b1e' 
  AND token = 'axRHoZ/ouZ8wnojZQNppKZPj5jdY0dGcAqUfePdthzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}