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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a838e8c13c241c05ad243f4e61abc412f0b2abdee8c0e03e974b2322b062cc77' 
  AND token = 'IxZNc/vuOPttGpOZiaWMa1uQDtHGelX/x6GUIfZSFoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}